A Nanocomposite Competent to Overcome Solubility and Permeation Issues of Capsaicin and Thiocolchicoside Simultaneously in Gout Management: Fabrication of Nanocubosomes

    March 2024 in “ Saudi Pharmaceutical Journal ”
    Barkat Ali Khan, Falak Naz, Ali Alqahtani, Muhammad Khalid Khan
    Studysummary This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
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    Research cited in this study 2

    1. Preparation and Optimization of Aloe Ferox Gel Loaded with Finasteride-Oregano Oil Nanocubosomes for Treatment of Alopecia Drug Delivery · 2022
    2. Omega 3 Fatty Acid-Enriched Nanoemulsion of Thiocolchicoside for Transdermal Delivery: Formulation, Characterization, and Absorption Studies Drug delivery · 2014