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January 1987 in “British Journal of Anaesthesia” Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
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January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
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April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
September 2019 in “Asian Journal of Pharmaceutical and Clinical Research” Teak seed extract is safe and reduces pain in mice.