Topical Minoxidil Does Not Act as an Antiandrogen in the Flank Organ of the Golden Syrian Hamster

January 1987 in “ Archives of Dermatology ”

Barbara A. Nuck

minoxidil antiandrogen flank organ androgen-dependent structures testosterone progesterone sebaceous glands hair follicle diameter Rogaine

Studysummary In this study, topical minoxidil did not show an antiandrogenic effect on androgen-dependent cutaneous structures in the golden Syrian hamster, suggesting it likely does not have this role in humans either.

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research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.

research Topical Antiandrogens: What Use in Dermatology?

5 citations , January 1985 in “Archives of Dermatology”

This article reviews the complex relationship between androgenic hormones and skin disorders, emphasizing the need for further innovative research to understand varying skin responses, but it reports no new findings.

research Topical Minoxidil for Hair Regrowth

80 citations , September 1984 in “Journal of The American Academy of Dermatology”

In this study, 5% topical minoxidil was observed to promote hair regrowth in some patients with androgenic alopecia, while no regrowth was noted in patients with alopecia areata.

research Alopecia Areata Treated With Topical Minoxidil

78 citations , April 1984 in “Archives of Dermatology”

This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.

research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

24 citations , May 1982 in “Biochemical Pharmacology”

These drugs cause hair growth without affecting testosterone or adrenal hormones.