Nitric Oxide-Releasing Topical Therapeutic Agent for Atopic Dermatitis

    Kimberly McHale, Joel Gil, S C Davis, Stan Hollenbach, Nathan Stasko
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    Studysummary In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.
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