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    Comparative Efficacy of Minoxidil Alone Versus Minoxidil Combined With Low-Level Laser Therapy in the Treatment of Androgenic Alopecia: A Systematic Review and Meta-Analysis

    January 2025 in “ Journal of Dermatological Treatment ”
    Abdulrahman Alosaimi, Abdullah Algarni, Abdulrahman Alharbi‎ … Waleed Alharbi
    Studysummary This systematic review and meta-analysis found that adding low-level laser therapy to minoxidil treatment for androgenic alopecia does not significantly enhance hair count or diameter compared to using minoxidil alone.
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    Research cited in this study 17

    1. Comparative Efficacy of 2% Minoxidil Alone Versus Combination With Low-Level Laser Therapy in Female Pattern Hair Loss: A Randomized Controlled Trial in Chinese Females Photodiagnosis and Photodynamic Therapy · 2024
    2. Efficacy of Minoxidil Combined With Photobiomodulation for the Treatment of Male Androgenetic Alopecia: A Double-Blind Half-Head Controlled Trial Lasers in Surgery and Medicine · 2021
    3. Efficacy and Safety of a New 10% Topical Minoxidil Versus 5% Topical Minoxidil and Placebo in the Treatment of Male Androgenetic Alopecia: A Trichoscopic Evaluation Journal of Dermatological Treatment · 2019
    4. HRQoL in Hair Loss-Affected Patients with Alopecia Areata, Androgenetic Alopecia, and Telogen Effluvium: The Role of Personality Traits and Psychosocial Anxiety Journal of The European Academy of Dermatology and Venereology · 2018
    5. The Effectiveness of Adding Low-Level Light Therapy to Minoxidil 5% Solution in the Treatment of Patients with Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    6. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    7. Minoxidil May Suppress Androgen Receptor-Related Functions Oncotarget · 2014
    8. Low-Level Laser Therapy for Treatment of Hair Loss Lasers in Surgery and Medicine · 2013
    9. Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial Dermatologic Surgery · 2013
    10. Alopecia: A Review of Laser and Light Therapies Dermatology Online Journal · 2012
    11. Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study Annals of Dermatology · 2012
    12. Types of Hair Loss and Treatment Options, Including the Novel Low-Level Light Therapy and Its Proposed Mechanism Southern Medical Journal · 2010
    13. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    14. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    15. Evaluation and Treatment of Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    16. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    17. Treatment of Hair Loss The New England Journal of Medicine · 1999