Efficacy of Scalp Cooling System Versus Chemical Cooling Cap in Preventing Chemotherapy-Induced Alopecia in Breast Cancer: A Prospective Randomized Trial

    April 2026 in “ The Breast ”
    Jie Zhang, Lize Wang, Yingjian He … Xinying Yu
    Studysummary This study found that both scalp cooling systems and chemical cooling caps effectively reduced chemotherapy-induced alopecia in early breast cancer patients, with scalp cooling showing better early efficacy but chemical cooling providing greater psychological and quality of life benefits.
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    Research cited in this study 3

    1. Scalp Hypothermia as a Preventative Measure for Chemotherapy-Induced Alopecia: A Review of Controlled Clinical Trials JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2017
    2. Chemotherapy-Induced Alopecia Management: Clinical Experience and Practical Advice Journal of Cosmetic Dermatology · 2017
    3. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009