Widespread Dystrophic-Anagen Alopecia and Drug Eruption Due to Usage of PEG-IFN Alpha-2a/Ribavirin Combination Therapy

    January 2014 in “ Hair therapy & transplantation ”
    Kamuran Türker, Ta B, AltnayS, Ta E
    Studysummary This case study reports the first extensively interpreted instance of dystrophic telogen effluvium potentially linked to pegylated interferon and ribavirin therapy for chronic hepatitis C, characterized through clinical and trichogram analysis.
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    Research cited in this study 11

    1. Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review Hepatology Research · 2012
    2. Drugs and Hair Loss: Mechanisms and Clinical Implications Dermatologic Clinics · 2012
    3. Telogen Effluvium Due to Recombinant Interferon Alpha-2b Dermatology · 2009
    4. Diffuse Hair Loss: Its Triggers and Management Cleveland Clinic Journal of Medicine · 2009
    5. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009
    6. A Review of Adverse Cutaneous Drug Reactions Resulting from the Use of Interferon and Ribavirin Canadian Journal of Gastroenterology · 2009
    7. Reversible Alopecia Universalis Secondary to PEG-Interferon Alpha-2b and Ribavirin Combination Therapy in a Patient with Chronic Hepatitis C Virus Infection European Journal of Gastroenterology & Hepatology · 2007
    8. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007
    9. Hair Loss Pattern Due to Chemotherapy-Induced Anagen Effluvium: A Cross-Sectional Observation Dermatology · 2007
    10. Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection British Journal of Dermatology · 2002
    11. Alopecia Areata During Interferon Alpha-2b and Ribavirin Therapy Dermatology · 2002