The Mouse Hairy Ears Mutation Exhibits an Extended Growth (Anagen) Phase in Hair Follicles and Altered Hoxc Gene Expression in the Ears

    November 2008 in “ Veterinary Dermatology ”
    Sarah E. Mentzer, John P. Sundberg, Alexander Awgulewitsch … Yun You
    Studysummary In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.
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    Research cited in this study 7

    1. A Position Effect on TRPS1 Is Associated with Ambras Syndrome in Humans and the Koala Phenotype in Mice Human molecular genetics online/Human molecular genetics · 2008
    2. FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    3. Hox in Hair Growth and Development Die Naturwissenschaften · 2003
    4. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    5. Hoxc13 Mutant Mice Lack External Hair Genes & Development · 1998
    6. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997
    7. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools Medical Entomology and Zoology · 1994