Bio-Analytical Method Development and Validation of Finasteride, Tadalafil, and Its Application to Pharmacokinetic Studies in Rat Plasma by Using LC-MS/MS

September 2024 in “ International Journal of Applied Pharmaceutics ”

Yesupadamu Rayinuthala, David Raju Medepalli, A. LAKSHMANARAO

finasteride tadalafil LC-MS/MS pharmacokinetic studies rat plasma Waters Symmetry C18 column perchloric acid acetonitrile Propecia Cialis

Studysummary This study describes a new LC-MS/MS method for analyzing Finasteride and Tadalafil, demonstrating system suitability, linearity, and accuracy in pharmacokinetic studies in rats, aligning with USFDA guidelines.

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