Global Research Trends in Extracellular Vesicle-Based Therapy for Regenerative Medicine: A Bibliometric Analysis (2014–2024)

This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.

This source reports that clinical trials using advanced Deep Brain Stimulation systems, augmented with AI to integrate kinematic data, eye tracking, and cognitive assessments, show promise in improving diagnostic accuracy and monitoring symptoms for patients with Parkinson's disease.

This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.

This review discusses pre-clinical research on ultrasound-mediated sonoporation for tissue regeneration and reports no clinical results; the authors suggest the method is safe and highlight challenges to clinical translation.

This perspective study suggests that plant-derived extracellular vesicles could advance the use of Ayurvedic medicinal plants in nanomedicine by enhancing their therapeutic potential and guiding future research.