Acellular Dermal Matrix Hydrogels Promote Healing of Radiation-Induced Skin Injury in a Rat Model
January 2024
in “
Journal of Materials Chemistry B
”
acellular dermal matrix ADM hydrogels radiation-induced skin injury RISI porcine dermis apoptosis epithelial thickness hair follicle regeneration angiogenesis vascular maturation M2 macrophage polarization pro-inflammatory cytokines IL-1β IL-6 anti-inflammatory cytokine IL-10 ADM hydrogels skin injury wound healing inflammation cytokines
Studysummary In this study, acellular dermal matrix hydrogels significantly improved healing in a rat model of radiation-induced skin injury by promoting angiogenesis and modulating inflammation, suggesting potential as a novel treatment for this common radiotherapy complication.
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