Reconstitution of Full-Thickness Skin by Microcolumn Grafting

    June 2016 in “ Journal of Tissue Engineering and Regenerative Medicine ”
    Joshua Tam, Ying Wang, Linh N. Vuong … R. Rox Anderson
    Studysummary This study demonstrated that implanting μm-scale full-thickness columns of human skin tissue into immunodeficient mice restored key features of normal human skin, suggesting potential for human wound repair with minimal donor site morbidity.
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    Research cited in this study 5

    1. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    2. Micro-Mechanical Fractional Skin Rejuvenation Plastic & Reconstructive Surgery · 2013
    3. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    4. Induction of De Novo Hair Regeneration in Scars After Fractionated Carbon Dioxide Laser Therapy in Three Patients Dermatologic Surgery · 2011
    5. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007