Hyperandrogenism: Acne and Hirsutism

    January 2016 in “ Springer eBooks
    M. Blake Evans, Micah J. Hill
    From the encyclopedia
    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Cyproterone →

    a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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    Studysummary This article reviews causes and treatments of hyperandrogenism, including hirsutism and acne, but presents no new clinical findings.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document from 2015 discussed hyperandrogenism, a common condition in women that often results in hirsutism (excessive hair growth) and acne. The causes of hyperandrogenism can include polycystic ovarian syndrome (PCOS), idiopathic hirsutism, congenital adrenal hyperplasia (CAH), ovarian and adrenal tumors, Cushing’s disease, and certain medications. The severity of hirsutism varies among patients, but treatment should be offered to those who desire it, regardless of severity. Treatment methods can include weight reduction, hair removal, oral contraceptive pills, and antiandrogen medications such as spironolactone, finasteride, cyproterone acetate, flutamide, and eflornithine. Acne treatments can include topical retinoids, topical antimicrobials like benzoyl peroxide, topical antibiotics like erythromycin, clindamycin, sulfacetamide, dapsone, or oral isotretinoin.
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