March 2016 in “West Indian medical journal” This study found no statistically significant relationship between androgenic alopecia and the PON1 ML55 and QR192 genetic polymorphisms, despite a higher frequency of the PON 55 L allele in patients.
June 2025 in “Turkish Journal of Dermatology” This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.
July 2022 in “International Journal of Contemporary Medicine” This study found that patients with alopecia areata have significantly lower serum PON1 levels compared to controls, indicating a potential link between oxidative stress and the pathogenesis of the disease.
October 2023 in “Benha Journal of Applied Sciences” This study found that male patients with androgenetic alopecia had lower serum levels of the antioxidant enzyme paraoxonase 1 compared to healthy controls.
November 2021 in “International Journal of Trichology” This study found that androgenetic alopecia patients had significantly lower serum levels of paraoxonase 1, which correlated with disease severity and suggests a role of oxidative stress in its pathogenesis.
