threonine
Research
20 / 963 resultsresearch Preventable Effect of L-Threonate, an Ascorbate Metabolite, on Androgen-Driven Balding via Repression of Dihydrotestosterone-Induced Dickkopf-1 Expression in Human Hair Dermal Papilla Cells
In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.
research Preventable Effect of L-Threonate, an Ascorbate Metabolite, on Androgen-Driven Balding via Repression of Dihydrotestosterone-Induced Dickkopf-1 Expression in Human Hair Dermal Papilla Cells
In this study, L-threonate was observed to inhibit DHT-induced DKK-1 expression in dermal papilla cells and reverse DHT's inhibitory effects on outer root sheath cell growth, suggesting potential as a treatment for androgen-driven balding.
research A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species
This study developed a rapid method to extract proteins from human hair, revealing phosphorylation on serine and threonine residues in alpha-keratins and matrix proteins.
research Identification of the Keratin-Associated Protein 13-3 (KAP13-3) Gene in Sheep
In this study, researchers identified five unique sequences of the ovine KAP13-3 gene, with potential implications for wool traits due to observed amino acid changes.
research Protein and Amino Acid Composition of Hair from Mice Carrying the Naked (N) Gene
In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.
research Solid State NMR of Isotope Labeled Murine Fur: A Powerful Tool to Study Atomic Level Keratin Structure and Treatment Effects
This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.
research Molecular Characterization of Caprine KRTAP13-3 in Liaoning Cashmere Goat in China
This study identified eight alleles of the caprine KAP13-3 gene in cashmere goats, which could influence gene expression and cashmere fiber characteristics.
research The N- And C-Terminal End Groups Of Hair Keratin
This study identified the same N-terminal and C-terminal amino acids in human and horse hair as previously found in wool and feather keratin.
research Human Hair Proteins as Natural Reactive Oxygen Species Scavengers for In Vitro Applications
This study demonstrated that human hair keratins have strong antioxidative properties, providing protection against oxidative stress in human dermal fibroblasts, suggesting their potential as antioxidizing supplements.
research Identification of the Novel Membrane-Associated Protein AgK114 on Hamster Keratinocytes Recognized by a Monoclonal Antibody K114
In this study, AgK114 was found to be transiently induced in hamster epidermal keratinocytes following skin damage, suggesting its role in the recovery process after injury.
research Investigating the Relationship Between the Hair Fiber Proteome and Hair Quality
In this study, researchers linked hair composition and mechanical properties to perceived hair quality, suggesting that hair quality may be genetically determined.
research Human Hair Production by Scalp Samples Grafted onto Nude Mice: Biochemical Data on Normal Human Hair and the Genetic Defect Trichothiodystrophy
This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected human scalp hair over extended periods.
research Carbonylation of Hair Proteins: A Robust Biomarker of Molecular and Structural Oxidative Damage in Hair Fibers
This research studied European human hair, finding that cysteic acid and protein carbonylation increased with both chemical and photochemical oxidation. Protein carbonylation was highlighted as a more sensitive marker for photochemical oxidation, providing better in situ visualization of hair damage than cysteic acid.
research Comparative Studies of Hair Shaft Components Between Healthy and Diseased Donors
This study examined hair mineral and free amino acid components in various diseases and found that when using effect size analysis, specific components related to diabetes and other conditions were identified, suggesting their potential as novel health indicators.
research Identification and Characterization of the Hamster Polyomavirus Middle T Antigen
In this study, researchers found that the ability of hamster polyomavirus to cause lymphoid tumors in Syrian hamsters may be linked to its association with the tyrosine kinase p59fyn.
research Are STK11 Polymorphisms a Predictor of the Response to Metformin in Polycystic Ovarian Syndrome?
This study concluded that STK11 gene polymorphisms were not predictive of metformin response in women with PCOS, though they may influence alopecia and hirsutism.
research Novel Biallelic RIPK4 Mutations Cause Ectodermal Dysplasia with Cutaneous Syndactyly
This study identifies two previously unreported pathogenic RIPK4 gene variants, suggesting a functional link with cell adhesion molecules in ectodermal dysplasias.
research Assessment of Tissue Levels of Dickkopf-1 in Androgenetic Alopecia and Alopecia Areata
This study found elevated tissue levels of DKK-1 in patients with both androgenetic alopecia and alopecia areata compared to controls, suggesting DKK-1 as a potential therapeutic target for these conditions.
research Effects of Baicalin on Alopecia and the Associated Mechanism
The researchers concluded that baicalin may promote hair growth and follicle proliferation by activating the AKT pathway, suggesting its potential as a treatment for alopecia.
research Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle
In this study, physiological levels of free T3 significantly enhanced the survival of human hair follicles in vitro.