Wanting to hear from long term RU users
    2/3/2026

    From the encyclopedia
    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 RU58841 (topical) 7 months
    💊 Dutasteride (oral) since 2018
    💧 Minoxidil (topical) 7 months
    the tone is 😀 positive with making a difference results.

    Other terms

    RU58841, combined with Dutasteride and topical Minoxidil, is helping users slow hair loss. Long-term users report positive results without significant side effects.
    View this post in the Community →

    Similar Community Posts Join

    6 / 6 results

      community M24, 1 year pictures using oral dut & topical minoxidil sulfate

       35 upvotes 3 weeks ago
      A user shared their experience using oral dutasteride and topical minoxidil sulfate for hair loss, noting little improvement and considering a hair transplant. Others suggested trying oral minoxidil, RU58841, microneedling, and ensuring medication is sourced from a legitimate pharmacy.

      community Dr Kyle Gillett on topical Dutasteride

      in Finasteride/Dutasteride  56 upvotes 3 years ago
      The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

      community Rate my regimen: 20yo/M looking for advice

      in Satire  145 upvotes 4 years ago
      A 20 year old male discussing his hair loss regimen, which includes using topical dutasteride, rogaine, RU58841, minoxidil and Avodart pills as well as scalp massage, stabbing head with steak knife, counting shed hairs under a hair net and sending them to a lab for analysis. Suggestions from other users include scalping method and switching to saw palmetto and zinc supplements.

      community Any experience with dutasteride 2.5mg dose? (Or any dose more than 0.5 mg).

       2 upvotes 8 months ago
      A user with aggressive androgenic alopecia is considering increasing their dutasteride dose from 0.5 mg to potentially 2.5 mg, while already using oral minoxidil, Nizoral, RU-58841, and dermapen. They are seeking advice on the effectiveness and side effects of higher dutasteride doses, with suggestions to consult a dermatologist and consider a higher Nizoral concentration.

    Related Research

    6 / 6 results
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      Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

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      70 citations , February 2015 in “Expert Opinion on Drug Discovery”
      This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
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      Therapeutic Strategies for Treating Hair Loss

      research Therapeutic strategies for treating hair loss

      42 citations , March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.