Dut and topical min for 8 years, losing ground even after adding oral min 6 months ago and no more shedding
    Update 4/21/2026

    From the encyclopedia
    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5mg daily 8 years
    💧 Minoxidil (topical) 8 years
    💊 Minoxidil (oral) 2.5mg 6 months
    the tone is 😞 negative with no growth results.

    Other terms

    The user has been using oral dutasteride and topical minoxidil for 8 years, added oral minoxidil 6 months ago, but continues to experience hair thinning despite reduced shedding. They are considering checking iron levels, switching medication brands, and exploring other treatments like RU58841.
    View this post in the Community →

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      community Naturally high T (1,100+) causing diffuse thinning while on Dut

       22 upvotes 5 months ago
      A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

      community Oral Dut/Minoxidil for two years - no results.

       102 upvotes 1 year ago
      The user has used oral Dutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.

      community Dutasteride not working - is this the end now?!

      in Chat  4 upvotes 5 months ago
      The user is experiencing ongoing hair loss despite using treatments like topical and oral finasteride, dutasteride, oral minoxidil, and RU58841. They are advised to consider a scalp biopsy and blood tests to determine the underlying cause, as their hair loss may not be related to DHT.

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