How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment? Treatment 11/5/2025
The user is considering adding Pyrilutamide or Alfatradiol as a topical treatment for hair loss after oral Finasteride and Dutasteride became less effective. Other users suggest Pyrilutamide for its safety profile, while one user shares positive experiences with RU58841 for reducing scalp itch and improving hairline.
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5 / 971 resultscommunity 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭
A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.
community Why is the general consensus that if you can’t tolerate 5AR Inhibitors you’re “cooked”?
Alternatives to finasteride for hair loss include minoxidil, alfatrodial, fluridil, pyrilutamide, and Nizoral. These treatments may not be as effective as finasteride but can help slow hair loss progression.
community Kintors 1% Pyrilutamide comes in October/November
Kintor's 1% Pyrilutamide will be released in October/November. The user cannot tolerate finasteride.
community 7 years of maintenance without finasteride
The user maintained their hair for 7 years using alfatradiol, fluridil (later switched to pyrilutamide), minoxidil 5%, and Nizoral shampoo without finasteride due to side effects. Despite some family history of hair loss, the user believes their hair loss is not aggressive.
community Pyrilutamide is literally my only hope
Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.
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