Pyrludimide (KX-826) actual drug could work better than the cosmetic version
    7/18/2026

    From the encyclopedia
    Pyrilutamide โ†’

    highly targeted anti-androgen that might have minimal systemic effects

    Minoxidil โ†’

    An essential vasodilator with some anti-androgenic effects

    At a glance
    In this general discussion post, the primary subjects mentioned are
    ๐Ÿ’ง Pyrilutamide (topical) 0.5% or 0.9% or 1.0%
    โ€ข Minoxidil
    the tone is ๐Ÿ˜ neutral with no improvement results.

    Other terms

    The conversation discusses the effectiveness of different versions of Pyrilutamide (KX-826) for hair loss, with skepticism about the cosmetic versions and interest in a new 1.0% version. Some users report success with products from Koshine, while others criticize Pyrilutamide's effectiveness compared to Minoxidil.
    View this post in the Community โ†’

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    6 / 6 results

      community Using Topical Minoxidil And Pyrilutamide Together

      in Treatment  1 upvotes 2 years ago
      Mixing 1ml of topical Minoxidil and Pyrilutamide (2ml total) together in a container and applying immediately is being discussed. The concern is whether this method degrades or compromises the efficacy of either compound.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community My personal experience/observations fighting AGA seriously for 5 years

       50 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

      community Fuck it, Iโ€™m ordering Pyri Topical

      in Product  12 upvotes 2 years ago
      A user plans to order Pyrilutamide for hair loss after losing ground on finasteride. Another user advises against buying from Hairliciously, suggesting Amazon instead.

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    6 / 6 results