Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)
    4/6/2026

    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5 mg daily (increased to 1 mg daily) daily since Sept 2021
    💊 Minoxidil (oral) 5 mg/day (2.5 mg twice daily) daily since ~2022
    💧 RU58841 (topical) 200 mg nightly (5%) nightly since July 2025
    💧 Ketoconazole shampoo (topical) 2–3x/week since 2021
    💧 Microneedling (topical) 0.75 mm 2x/month since 2024
    💧 Low-level laser therapy (topical) 5x/week (~25 min sessions) since May 2025
    the tone is 😞 negative with no improvement results.

    Other terms

    The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.
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