Highly experimental stack! Self Study Coming!
    4/7/2026

    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Pyrilutamide →

    highly targeted anti-androgen that might have minimal systemic effects

    PP405 →

    mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

    At a glance
    In this hair loss treatment regimen post, the primary subjects mentioned are
    💧 Micro Needling (topical) 1.5mm once weekly months 1-6
    💧 Minoxidil (topical) twice daily months 1-6
    • Pyrilutamide months 1-6
    💧 Ketoconazole shampoo (topical) 2% 2-3x weekly months 1-6
    • PP405 months 1-6
    💧 Topical Melatonin (topical) months 1-6
    • Bimatoprost months 1-6
    • Saw Palmetto+Pumpkin Seed Oil high concentration extract months 7-9
    • SAM-002 or VDPHL01 months 7-9
    💧 Caffeine shampoo (topical) 1% 2-3x weekly months 7-9
    the tone is 😐 neutral.

    Other terms

    A 19-year-old plans to use an experimental hair loss treatment stack including micro-needling, Minoxidil, Pyrilutamide, Ketoconazole shampoo, and other unreleased compounds like PP405. Users advise against using unverified treatments and suggest sticking to proven options like Finasteride, with some recommending topical application to avoid side effects.
    View this post in the Community →

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