Apparently azelaic acid inhibits DHT, what are the side effects?
    4/2/2021

    From the encyclopedia
    Azelaic Acid →

    acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Azelaic Acid (topical)
    💊 Finasteride (oral)
    the tone is 😐 neutral.

    Other terms

    Azelaic acid is discussed as a DHT inhibitor with no reported sexual side effects, but its effectiveness and absorption as a topical treatment are questioned. The user is interested in azelaic acid due to concerns about finasteride affecting penile health.
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    5 / 5 results

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Side effects of topical azelaic acid?

       4 upvotes 5 years ago
      Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.

      community Topical Azelaic acid efficacy?

       5 upvotes 3 years ago
      The user switched from Forhims to Numan topical treatment for hair loss, which includes finasteride, minoxidil, and azelaic acid, and is questioning the effectiveness of azelaic acid in the formula. They also mentioned that Numan has a higher concentration of minoxidil compared to their previous product.

      community Can I Use Topical Azelaic Acid & Oral Finasteride At The Same Time?

       2 upvotes 2 years ago
      A user is considering using a topical Minoxidil solution with tretinoin and Azelaic Acid while taking oral Finasteride and is seeking advice on safety and effectiveness. They have been using Minoxidil for 10 years with mild results and oral Finasteride for a year with some positive changes.

      community Theoretically won't this be better than finasteride? Azelaic acid + zinc

       9 upvotes 3 years ago
      The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.

    Related Research

    6 / 6 results
      Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

      research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

      11 citations , December 2018 in “Assay and Drug Development Technologies”
      This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.
      Androgenic Alopecia: Case Study and Treatment Analysis

      research Androgenic Alopecia

      8 citations , September 2010 in “Journal of Men's Health”
      This article reviews the pathophysiology, diagnosis, and treatment of androgenic alopecia but reports no new clinical findings.

      research Topical and Systemic Therapies in Melasma: A Systematic Review

      10 citations , October 2023 in “Indian Dermatology Online Journal”
      In this study, the researchers highlighted the availability of new topical and systemic agents with varied mechanisms for treatment, emphasizing that the choice of agent should be tailored to individual needs and the options available in different countries.