Almost 4 months, before and after of pyrilutamide .5% once daily
    5/13/2026

    From the encyclopedia
    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    Alfatradiol →

    Weak form of estrogen applied to the scalp

    Pyrilutamide →

    Experimental topical anti-androgen, also known as KX-826

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💧 Minoxidil (topical) 5% once daily 7 years
    💧 Alfatradiol (topical) 0.025% once daily almost 4 months
    💧 Pyrilutamide (topical) 0.5% once daily almost 4 months
    💧 Nizoral (topical) 2% twice a week almost 4 months
    the tone is 😀 positive with significant hair regrowth results.

    Other terms

    The user experienced significant hair regrowth using a combination of minoxidil, alfatradiol, pyrilutamide, and nizoral, despite previous intolerance to finasteride. They emphasize the importance of consistency in treatment and are optimistic about the results, noting no side effects so far.
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    5 / 5 results

      community Six month results of pyrilutamide and Alfatrodial

       30 upvotes 2 months ago
      The user experienced significant hair regrowth after using pyrilutamide and alfatrodial for six months, alongside minoxidil and nizoral shampoo, without any side effects. They previously stopped finasteride due to side effects and found the new regimen effective in improving their hairline.

      community Guys I actually can’t believe pyrilutamide is actually working!!

       29 upvotes 4 months ago
      Hair regrowth was achieved using minoxidil, nizoral, alfatrodial, and pyrilutamide after finasteride caused side effects. The user recommends this combination for those who can't tolerate 5AR inhibitors, stressing consistent use.

      community 7 years of maintenance without finasteride

      in Progress Pictures  17 upvotes 11 months ago
      The user maintained their hair for 7 years using alfatradiol, fluridil (later switched to pyrilutamide), minoxidil 5%, and Nizoral shampoo without finasteride due to side effects. Despite some family history of hair loss, the user believes their hair loss is not aggressive.

      community What I’ve learned From 8 Months on Pyrilutamide

       11 upvotes 5 days ago
      Pyrilutamide helps maintain hair density but is less effective than finasteride and needs consistent use. It works best with minoxidil, alfatrodial, and nizoral, though it is costly and inconvenient.

      community After 7 years on minoxidil 5% foam how bad is it? (28 year old male)

      in Is this regrowth? 6 months ago
      A 28-year-old male, who has been using minoxidil for 7 years, is concerned about hair miniaturization and is considering adding pyrilutamide, alfatradiol, and nizoral to his regimen after experiencing side effects from finasteride. Despite concerns, others reassure him that his hairline appears normal for his age, and he is likely around a Norwood 1.5.

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    6 / 6 results