After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily
    Progress Pictures 11/18/2025

    From the encyclopedia
    Estradiol β†’

    Estrogen hormone, prescribed in tablet, patch and gel forms

    Minoxidil β†’

    Vasodilator used on the scalp and, at low doses, as a tablet

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    β€’ Estradiol (sublingual) 2mg daily 3 months
    πŸ’Š Minoxidil (oral) 2.5mg daily 3 months
    the tone is πŸ˜€ positive with significant progress results.

    Other terms

    A person transitioning is using 2mg sublingual estradiol and 2.5mg oral minoxidil daily for hair regrowth, noting significant progress in three months. They plan to increase estrogen dosage and consider adding dutasteride, discussing the effects and challenges of transitioning.
    View this post in the Community β†’

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    5 / 5 results

      community 5 months into 0.5mg Dutasteride 3x a week + 5mg Oral Minoxidil

      in Progress Pictures  58 upvotes 8 months ago
      A user is treating hair loss with 0.5mg Dutasteride three times a week, 5mg oral Minoxidil daily, and topical finasteride and minoxidil, seeing some improvement but insufficient density. They are considering increasing Dutasteride dosage and addressing high estradiol levels, while also trying to quit vaping.

      community Dermatologist denied prescribing oral dutasteride because it’s not FDA approved BUT did prescribe ORAL minoxidil πŸ˜‚

      in Finasteride/Dutasteride  31 upvotes 2 years ago
      A 22-year-old male has been using oral finasteride for a year with no improvement in hair loss and was denied dutasteride by a dermatologist due to FDA approval issues but was prescribed oral minoxidil instead. The user is seeking advice on whether to switch to dutasteride, continue finasteride, or add minoxidil.

      community Oral minoxidil gives hair everywhere except scalp,plss help

      in Minoxidil  41 upvotes 1 year ago
      Oral minoxidil is causing body hair growth but not improving scalp hair, despite using dutasteride and finasteride. Users suggest waiting longer for results, checking vitamin levels, and considering additional treatments like topical minoxidil, dermarolling, and supplements.

      community M24, 1 year pictures using oral dut & topical minoxidil sulfate

       35 upvotes 1 month ago
      A user shared their experience using oral dutasteride and topical minoxidil sulfate for hair loss, noting little improvement and considering a hair transplant. Others suggested trying oral minoxidil, RU58841, microneedling, and ensuring medication is sourced from a legitimate pharmacy.

      community 1 year of finasteride, minoxidil and dutasteride

       902 upvotes 2 months ago
      A 26-year-old shared their successful hair regrowth journey using finasteride, minoxidil, and dutasteride, along with a custom minoxidil solution containing progesterone, cortisone, alpha 5 estradiol, menthol, caffeine, and melatonin. They experienced no side effects but noted that stopping the medications would reverse the progress.

    Related Research

    6 / 6 results

      research CLINICAL UPDATES IN HAIR

      19 citations , January 1997 in “Dermatologic Clinics”
      This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.

      research Safety concerns when using novel medications to treat alopecia

      23 citations , October 2018 in “Expert Opinion on Drug Safety”
      This review discusses the safety concerns associated with new treatments for non-scarring alopecias, highlighting that while these therapies such as JAK inhibitors and oral minoxidil show efficacy in hair regrowth, their safety profiles vary significantly, requiring careful consideration of benefits and risks.

      research Treatment options for alopecia: an update, looking to the future

      35 citations , May 2012 in “Expert Opinion on Pharmacotherapy”
      This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.

      research Hormonal therapy in female pattern hair loss

      21 citations , February 2017 in “International Journal of Women's Dermatology”
      This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.