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Glossary Y chromosome

sex chromosome determining male biological characteristics in humans

The Y chromosome is one of the two sex chromosomes in humans, the other being the X chromosome. It is typically found in males and carries genes that are crucial for the development of male reproductive tissues and secondary sexual characteristics. The presence of a Y chromosome generally determines male biological sex, as it contains the SRY gene, which triggers male development.

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research Molecular mechanisms of Y chromosome loss and UTY gene activity

February 2024 in “Future science OA”

This commentary highlights that the loss of the Y chromosome may disrupt UTY/TLE1-RUNX1 interactions, potentially impacting male hematopoietic cell development and leading to conditions like acute myeloid leukemia and T-cell acute lymphoblast leukemia.

research Loss of the Y Chromosome: A Review of Molecular Mechanisms, Age Inference, and Implications for Men’s Health

13 citations , April 2024 in “International Journal of Molecular Sciences”

This literature review highlights the importance of understanding the mechanisms behind the gradual mosaic loss of the Y chromosome (mLOY) in men, its association with various health conditions like cardiovascular diseases and cancer, and its potential as a marker for age inference.

research The Who’s, What’s, and “Y”s: Y Sex Chromosome Loss and Methylation for Analysis in Male Aging and Mortality and Forensic Science Applications

November 2024 in “Forensic Sciences”

This review highlights the potential for using the Y chromosome in epigenetic analyses to better understand male-specific aging and disease mechanisms.

research SUN-208 Rare Case of 47XXY/46XX Mosaic Klinefelter Syndrome

April 2019 in “Journal of the Endocrine Society”

This case report described a 39-year-old male with 47XXY/46XX mosaic Klinefelter syndrome who presented with common features of the condition and male pattern baldness seen in his family.

research 4th Intercontinental Meeting of Hair Research Societies 2004 The "World of Hair"

1 citations , May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft”

This article from the 4th Intercontinental Meeting of Hair Research Societies provides no abstract or new findings.

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community Why not just take the drugs before hair loss?

in Chat 123 upvotes 6 months ago

Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.

community Balding while your father has a full head of hair must suck

in Finasteride/Dutasteride 261 upvotes 1 year ago

Unexpected hair loss despite family members having full hair. Treatments include finasteride, minoxidil, and dutasteride.

community IVF process on Finasteride and effects of stopping finasteride.

138 upvotes 9 months ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community 1 Month on Dutasteride (0.5mg) + Supplements – Seeing Thickness But No New Hairs Yet. Is That Normal?

in Is this regrowth? 83 upvotes 1 year ago

A 31-year-old woman is using Dutasteride (0.5mg daily) and supplements like a multivitamin, Herbadal, pumpkin seed oil, and vitamin D for genetic hair loss, noticing thicker hair but no new growth after one month. She is considering adding minoxidil and is aware of Dutasteride's risks, especially regarding pregnancy.

community Hair Restoration Log (Weekly 1.5 mm microneedling + QOD 0.5 mg Finasteride + Daily 50 mg 5% RU58841)

2 upvotes 5 years ago

The user experienced side effects from daily 1 mg Finasteride and switched to 0.5 mg every other day, supplemented with creatine, tongkat ali, tribulus terrestris, vitamin D3, bromantane, l-tyrosine, and caffeine. They also use weekly 1.5 mm microneedling and daily 50 mg RU58841, except on microneedling days, to manage hair loss.

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