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research 1329 CENPV is a novel CYLD-interacting molecule regulating ciliary acetylated tubulin

April 2018 in “Journal of Investigative Dermatology”

In this study, researchers identified CENPV as a new CYLD interacting partner that localizes to primary cilia and regulates acetylated tubulin levels, offering insights into the pathogenesis of skin appendage tumors.

research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata

19 citations , January 2018 in “Scientific Reports”

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

research How a Bird Gets Its Feathers: Insights from Chromatin Looping

3 citations , June 2020 in “Developmental Cell”

This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.

research Albendazole-induced anagen effluvium: a brief literature review and our own experience

2 citations , January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)”

This article presents two cases of anagen effluvium following oral albendazole use and summarizes previously reported cases, suggesting this side effect may occur with this drug.

research Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients

48 citations , June 2014 in “Neurobiology of Disease”

This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.

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community Oral v topical Min & Dutasteride

16 upvotes 1 month ago

The user experienced hair loss after switching from topical to oral minoxidil and adding dutasteride, leading to doubts about its effectiveness. They are considering returning to RU58841 or topical minoxidil due to continued shedding and mental distress.

community Day 1 v 3 month progress. Topical Spray used in the UK.

68 upvotes 2 weeks ago

A user in the UK reports significant hair growth progress after three months using a topical spray containing Minoxidil, Finasteride, and Tretinoin, applied daily. They recommend the product from e-Surgery, noting no side effects and using Biotin shampoo every two days.

community Is 0.1%w/v topical fin overkill if taking oral 0.5mg fin?

in Finasteride/Dutasteride 2 upvotes 7 months ago

The conversation discusses whether using 0.1% topical finasteride alongside 0.5 mg oral finasteride is excessive, with suggestions to choose either oral or topical treatment. The user also uses 5% minoxidil and mentions concerns about alcohol-based solutions due to seborrheic dermatitis.

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