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Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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Frontline, gold standard treatment for combatting androgenic alopecia
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diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
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research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Fixing DNA errors is crucial to prevent skin cancer.
research Data from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
The study demonstrates that selective inactivation of ribonucleotide excision repair (RER) in mouse epidermis leads to spontaneous DNA damage, epidermal hyperproliferation, loss of hair follicle stem cells, and hair follicle function. This results in the development of keratinocyte intraepithelial neoplasia and invasive squamous cell carcinoma with complete penetrance, despite a strong type I interferon response and skin inflammation. These findings suggest that impairments in RER-mediated genome maintenance could be a significant factor in promoting tumor development in human cancer.
research Data from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
The study demonstrates that selective inactivation of ribonucleotide excision repair (RER) in mouse epidermis leads to spontaneous DNA damage, epidermal hyperproliferation, loss of hair follicle stem cells, and hair follicle function. This condition results in the development of keratinocyte intraepithelial neoplasia and invasive squamous cell carcinoma with complete penetrance, despite a strong type I interferon response and skin inflammation. These findings suggest that impairments in RER-mediated genome maintenance could be a significant factor in promoting tumor development in human cancer.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis
The study investigates gene expression in hair follicles affected by chronic discoid lupus erythematosus (CDLE) using bioinformatics methods. By analyzing data from 4 healthy and 7 CDLE-affected hair follicles, and validating with 13 healthy and 47 CDLE-affected scalp samples, the researchers identified key genes through differential expression and WGCNA. These genes, associated with type I interferon response and RIG-1 and IL-17 signaling pathways, were significantly upregulated in both hair follicles and skin tissues. The study also suggests the involvement of follicular helper T cells (Tfhs) in the disease process.
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5 / 1000+ resultscommunity Topical Dutasteride is Here.
The availability of Topical Dutasteride, a potential treatment for hair loss, which can be purchased without prescription from MinoxidilMax. Other treatments discussed include Topical Finasteride and PRP injections, with discussion around dosage, efficacy, side-effects and safety.
community Minoxidil seems logistically impossible and impractical to use
The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.
community Transient and Permanent Effects of Finasteride Use
Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.
community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.
A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.
community Peppermint Oil: If you stop using it, will you lose everything you gained? Like Minoxidil?
People discussed their experiences with peppermint oil for hair loss, with mixed results. Some users reported no hair loss after stopping peppermint oil, while others experienced shedding; one user noted improved scalp health when mixing it with minoxidil.