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    GlossaryT helper 1 cell

    immune cells that activate macrophages to fight intracellular pathogens

    T helper 1 cells, often abbreviated as Th1 cells, are a type of immune cell that play a crucial role in the body's defense against intracellular pathogens like viruses and certain bacteria. They produce cytokines, such as interferon-gamma (IFN-γ), which activate macrophages and enhance the ability of other immune cells to destroy infected cells.

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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  212 upvotes 5 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community Expectations control for SCUBE3

      in Research/Science  20 upvotes 7 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       23 upvotes 6 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.