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GlossaryTumor Necrosis Factor

protein involved in inflammation and immune system regulation

Tumor Necrosis Factor (TNF), also known as TNF-alpha, is a protein produced by the immune system that plays a crucial role in inflammation and the body's response to infection. It helps regulate immune cells, but excessive TNF can lead to chronic inflammatory diseases such as rheumatoid arthritis and psoriasis.

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Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

research Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

48 citations, January 2014 in “Dermatology Online Journal”

New treatments for Dissecting cellulitis show promise, but more research is needed to understand the disease and establish a standard treatment plan.

research A Case of Recalcitrant Pediatric Vogt-Koyanagi-Harada Disease Successfully Controlled with Adalimumab

15 citations, January 2019 in “Journal of the Formosan Medical Association”

Adalimumab helped control a child's severe eye disease when other treatments failed.

Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

21 citations, April 2010 in “Veterinary Dermatology”

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

research Update on Hidradenitis Suppurativa: Connecting the Tracts

36 citations, December 2014 in “F1000 prime reports”

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

research Anticytokine Therapy, Particularly Anti-IFN-γ, in Th1-Mediated Autoimmune Diseases

9 citations, May 2005 in “Expert Review of Clinical Immunology”

Blocking interferon-gamma might help treat various autoimmune diseases.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Pyrilutamide 5 months results (before, after pics)

in Progress Pictures 193 upvotes 1 year ago

Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

community Did anybody not care at all about their hair until they started losing it?

in Chat 134 upvotes 1 month ago

People regret neglecting their hair until it started thinning, and they are now using treatments like finasteride, minoxidil, and microneedling. Some are considering stronger options like dutasteride due to mixed results.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 4 months ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community How soon is hair clone? Next five years?!

in Research/Science 15 upvotes 4 months ago

Hair cloning is humorously discussed as always being 5-7 years away, with skepticism about its near-term availability. Gene editing to reactivate dormant follicles is suggested as a more likely solution within the next ten years.

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