learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
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Tracking 10 products like 28 Minoxidil Serum, 38 Roman Hair Solution Rx, 109 FOLLICS FR07, 110 FOLLICS FR10 and 112 FOLLICS FR15 from by companies like Hims, Roman and Minoxidil Express. View all 10 products »Learn
5 / 63 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
Research
5 / 1000+ results
research Alopecia Areata Exhibits Cutaneous And Systemic OX40 Activation Across Atopic Backgrounds
Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.
research Genome-Wide Gene Expression Dataset Used to Identify Potential Therapeutic Targets in Androgenetic Alopecia
Five molecular elements identified as potential future targets for hair loss therapy.
research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis
Future acne treatments should aggressively target inflammation to prevent scarring.
research Grand Challenges in Dermatologic Drug Discovery: Four Priorities to Transform Skin Disease Treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
research Targeting Olfactory Receptor OR2AT4: An Innovative Aptamer-Based Treatment for Hair Growth Promotion
A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.
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5 / 1000+ resultscommunity Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway
A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.
community Pelage, PP405, is creating a database for potential new trial volunteers
PP405 is a new hair loss treatment targeting dormant hair follicles, with ongoing trials. Some users consider stopping finasteride and minoxidil to join trials, while others doubt its effectiveness.
community Verteporfin and Microneedling
by
nkrata
in Treatments 1 year ago Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
community TWIST-1 and the cure: Is it really that easy?
TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA
The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.