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Research

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research Algorithmic approach to the treatment of frontal fibrosing alopecia: A systematic review

8 citations , October 2018 in “Journal of The American Academy of Dermatology”

This study evaluated treatments for frontal fibrosing alopecia and found hydroxychloroquine and 5a-reductase inhibitors to be most effective, with 70-72% of patients experiencing stabilization or improvement, but limitations in treatment consistency and assessment methods remain.

research A consensus-based treatment algorithm for alopecia areata in adolescents and adults: integrating severity, quality of life, and disease dynamics

July 2026 in “Frontiers in Medicine”

This study describes a new treatment algorithm for alopecia areata that includes both disease severity and quality-of-life considerations, highlighting recent therapeutic advances and the need for future validation and access equity.

research Treatments for Dissecting Cellulitis of the Scalp: A Systematic Review and Treatment Algorithm

1 citations , September 2023 in “Dermatology and therapy”

This review explores the efficacy and safety of treatments for dissecting cellulitis of the scalp, revealing a predominance of case reports and series, and concludes that randomized controlled trials are needed for better evidence-based therapies.

research Brazilian Consensus on Psoriasis 2020 and Treatment Algorithm of the Brazilian Society of Dermatology

37 citations , September 2021 in “Anais Brasileiros de Dermatologia”

research Androgenetic Alopecia: Narrative Review of Current Therapies and Proposal of a Practical Algorithm for Pharmacological Treatment

May 2026 in “Actas Dermo-Sifiliográficas”

This review highlighted current treatments for androgenetic alopecia and proposed a management algorithm, noting additional therapies show effectiveness but lack inclusion in official guidelines due to the absence of randomized clinical trials.

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Community Join

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community PP405 timeframe ? Could it replace current treatments ?

in Update 34 upvotes 1 year ago

PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

community A flowchart showing how dermatologists treat male-pattern baldness from UpToDate, the industry-standard reference

in Treatment 12 upvotes 6 months ago

Dermatologists use treatments like oral minoxidil, finasteride, and RU58841 for male-pattern baldness, considering side effects and patient preferences. Photobiomodulation is noted as mildly effective but costly, while PRP is debated for its effectiveness compared to microneedling.

community How is there zero improvement with finding the cure?

in Research/Science 245 upvotes 7 months ago

Hair loss treatments have not advanced since 2018, with finasteride, minoxidil, and RU58841 still being the main options. A permanent cure is unlikely due to the profitability of ongoing treatments.

community kiierr laser cap.. does it actually work or just marketing hype?

in Chat 23 upvotes 2 months ago

Finasteride and minoxidil treatments plateaued after 10 months, leading users to explore additional options like microneedling and low-level laser therapy (LLT) caps, though many are skeptical of the effectiveness and marketing of LLT devices like Kiierr. Users express frustration with the lack of clear recommendations from dermatologists and the prevalence of marketing hype over genuine reviews.

community Average r/bald user complaining

401 upvotes 9 months ago

Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

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Learn

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learn Hair Transplant

How do I know which hair restoration treatment is right for me? Consult a professional for a personalized hair restoration treatment plan based on your needs.

learn Azelaic Acid

Is azelaic acid a treatment on its own or does it need supplements? One small randomised trial (26 women, no placebo) found no significant difference between 5% azelaic acid and 2% minoxidil in female pattern hair loss, which is too small to show they work equally well, and the anti-DHT rationale otherwise rests on in-vitro work. Community members generally describe azelaic acid as an add-on to minoxidil or finasteride rather than a standalone treatment.

learn Exosomes

Can an exosome treatment revive hair follicles that have stopped producing hair? Unproven. No controlled human study shows that exosomes revive dormant follicles, none can revive scarred ones, and no exosome product is FDA-approved.

learn Verteporfin

How does Verteporfin differ from standard treatments like minoxidil or finasteride? Verteporfin is an experimental treatment, while minoxidil and finasteride are FDA-approved therapies.

learn Scalp Micropigmentation

Will anyone notice my scalp micropigmentation treatment? Providers say well-done SMP is hard to spot, but results depend on the artist, and poor work can look artificial and is hard to correct (Park 2025, PMID 38822591).

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Clinics

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