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Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages

research Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages

April 2018 in “Journal of Investigative Dermatology”

The human skin's outer layer has more variety in cell types and development paths than previously thought.

research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny

338 citations , April 2001 in “Current Biology”

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

research Epidermal Keratinocyte Stem Cells: Their Maintenance and Regulation

25 citations , December 1992 in “Seminars in cell biology”

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

research Immunolocalization of Telomerases in Human Hairs Identifies Proliferating Cells in the Bulb Matrix and Outer Root Sheath

March 2024 in “Tissue and cell/Tissue & cell”

Telomerase-positive cells are mainly in the bulb matrix and outer root sheath of hair follicles.

research Colon Cancer Stem Cells: Promise of Targeted Therapy

411 citations , April 2010 in “Gastroenterology”

Targeting colon cancer stem cells might lead to better treatment results.

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 64 upvotes 5 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 196 upvotes 9 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community What's your option on complementary treatment

in Product 3 upvotes 1 year ago

The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

community Has anyone tried Exosomes from Musely or somewhere else?

in Hair Systems 11 upvotes 11 months ago

Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

community 2 months of Oral Minox and dutasteride for 3.22$ in India. How much does it cost you?

in Product 44 upvotes 1 year ago

The post discusses the cost of oral Minoxidil and dutasteride in India. Users compare prices and share experiences with international shipping and insurance coverage for Minoxidil and finasteride.

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