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Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

research Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

April 2023 in “Journal of Investigative Dermatology”

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

research 555 Dermal Single-Cell Atlas: A Novel Tool to Explore Fibroblast Heterogeneity

November 2022 in “Journal of Investigative Dermatology”

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

research Exploring Human Skin Aging at the Single-Cell Level

2 citations , February 2021 in “Developmental Cell”

Middle-aged skin shows aging signs, and quercetin might help delay them.

Transcriptomic Analysis of Human Skin Wound Healing and Rejuvenation Following Ablative Fractional Laser Treatment

research Transcriptomic Analysis of Human Skin Wound Healing and Rejuvenation Following Ablative Fractional Laser Treatment

24 citations , November 2021 in “PLoS ONE”

Ablative fractional laser treatment rejuvenates skin by altering gene expression and promoting wound healing and tissue regeneration.

Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying

research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying

13 citations , May 2022 in “Cell discovery”

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

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Community Join

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 59 upvotes 2 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Journey against alopecia - Finasteride 3 month

in Progress Pictures 17 upvotes 4 years ago

A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

community Bee venom better than minoxidil?

in Research/Science 1048 upvotes 2 weeks ago

Bee venom at 0.001% concentration was more effective than 2% minoxidil in promoting hair growth in mice, possibly due to increased growth factors and reduced inflammation. Caution is advised due to potential allergic reactions and the reliance on animal data.

community Results of Procyanidin B2 in clinical studies

in Treatment 12 upvotes 5 years ago

Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.