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Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

research Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

April 2023 in “Journal of Investigative Dermatology”

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

research 555 Dermal Single-Cell Atlas: A Novel Tool to Explore Fibroblast Heterogeneity

November 2022 in “Journal of Investigative Dermatology”

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

research Exploring Human Skin Aging at the Single-Cell Level

2 citations, February 2021 in “Developmental Cell”

Middle-aged skin shows aging signs, and quercetin might help delay them.

research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying

13 citations, May 2022 in “Cell discovery”

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs

35 citations, August 2021 in “npj Regenerative Medicine”

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

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community Results of Procyanidin B2 in clinical studies

in Treatment 10 upvotes 4 years ago

Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.