Search

for
Search:

Research

5 / 1000+ results

Hydroxychloroquine Modulates the Progression of Experimentally Induced Benign Prostatic Hyperplasia in Rats via Targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL Pathways: Computational and In Vivo Studies

research Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies

1 citations , June 2025 in “Scientific Reports”

In this study on testosterone-induced benign prostatic hyperplasia in rats, hydroxychloroquine significantly reduced prostate-related markers and enhanced therapeutic effects when combined with finasteride, suggesting potential as a new treatment approach.

research Trailing the Path to Preventive Oncology

1 citations , January 2018 in “Advances in cancer prevention”

This review discusses the preventable nature of many cancers due to modifiable risk factors and emphasizes the importance of preventive oncology in reducing the global cancer burden; it reports no new clinical results.

research TRAIL sensitization of PC3 prostate cancer cells by doxorubicin can be blocked by the anti-oxidant N-acetyl-cysteine or by the iron chelator deferoxamine

October 2006 in “Clinical Cancer Research”

This study found that doxorubicin-induced oxidative stress downregulates FLIPs and phosphorylates EF2, sensitizing prostate cancer cells to TRAIL; antioxidants may reduce doxorubicin's effectiveness, warranting further investigation.

research Tailoring bioinks of extrusion-based bioprinting for cutaneous wound healing

82 citations , January 2022 in “Bioactive Materials”

This review discusses extrusion-based bioprinting bioinks for skin regeneration, highlighting their current applications, limitations, and potential improvements, but reports no new experimental findings.

research A Splice Site Mutation in the Gene of the Human Type I Hair Keratin hHa1 Results in the Expression of a Tailless Keratin Isoform

28 citations , December 1997 in “Journal of Biological Chemistry”

This study found that the hHa1-t protein variant, caused by a genetic polymorphism in the hHa1 gene, forms functional keratin filaments despite lacking a complete nonhelical tail domain, explaining the absence of a pathological hair phenotype.

View more "trail" in research →

Community Join

5 / 1000+ results

community Trial at Fin perhaps Dut to follow

1 upvotes 2 weeks ago

The user tried finasteride for 6 months without noticeable improvement and is considering switching to dutasteride. They also used ketoconazole shampoo a few times a week.

community Trialing the probiotics BB536, PTA 6475 so you don’t have to

75 upvotes 1 year ago

Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

community Train your forehead and scalp muscles

in Research/Science 23 upvotes 1 year ago

Training scalp muscles to absorb more DHT is suggested as a hair loss solution, but users debate its effectiveness compared to medications like dutasteride and finasteride. Concerns about side effects of DHT blockers, such as reduced libido, are discussed, with some advocating for natural remedies like scalp massages and healthy living.

community Trial for TDM-105795 update from research office

16 upvotes 2 years ago

The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

community Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways.

4 upvotes 3 weeks ago

Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.

View more "trail" in community →

Learn

4 / 801 results

learn SCUBE3

What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth? No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

learn Scalp Micropigmentation

Will anyone notice my scalp micropigmentation treatment? Scalp micropigmentation is designed to be undetectable when done correctly.
Does scalp micropigmentation require maintenance? Scalp micropigmentation requires occasional touch-ups and sun protection for maintenance.
Can I use hair loss treatments (finasteride, minoxidil) after scalp micropigmentation? About half of clinics say finasteride can continue through scalp micropigmentation, and about half ask clients to pause topical minoxidil during the sessions and for roughly 30 days afterwards. That pause is clinic aftercare convention, not a label instruction - ask your prescriber first, because stopping minoxidil usually causes shedding.

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

View more "trail" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →