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research Follicular and percutaneous penetration pathways of topically applied minoxidil foam

74 citations , June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics”

This study found that hair follicles are a significant and efficient pathway for the absorption of topical minoxidil foam in humans, with faster blood detection when follicles are open.

research Topically applied minoxidil may cause fetal malformation: A case report

29 citations , December 2003 in “Teratology”

This case report describes fetal malformations and placental abnormalities in a pregnant woman who applied minoxidil topically, suggesting potential risks of its use during pregnancy.

research Topically Applied Minoxidil in Baldness

26 citations , March 1985 in “International Journal of Dermatology”

Minoxidil helps hair growth, but results vary.

research Topically Applied Tretinoin in the Treatment of Trichostasis Spinulosa

25 citations , September 1973 in “Archives of dermatology”

In this study, a daily topical application of a 0.05% tretinoin solution effectively removed dark plugs and resolved symptoms of trichostasis spinulosa.

research Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo

13 citations , December 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed that nicotinamide can effectively inhibit human hair growth and promote hair follicle regression in cultured human scalp models without negatively affecting epidermal vitality, suggesting its potential as a hair growth inhibitor in cosmetic applications.

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community Can topical tretinoin only applied to face (not hairline) exacerbate hair loss?

6 upvotes 8 months ago

Topical tretinoin applied to the face may exacerbate hair loss in some individuals, potentially triggering conditions like frontal fibrosing alopecia. Experiences vary, with some users reporting no impact on hair, while others experience significant hair loss.

community Topical Finasteride concetrations and amount applied

in Treatment 10 upvotes 1 year ago

Topical finasteride concentrations and application amounts are debated, with concerns that mainstream solutions may use arbitrary concentrations. A 0.25% solution with a specific application method is suggested as more appropriate than higher concentrations.

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learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn KY19382

How is KY19382 applied—topically or orally—for hair growth treatment? In every published study KY19382 has been applied topically, never taken orally; the work is preclinical (cells, cultured follicles and mice) and no human trial results have been published.

learn Setipiprant

Is Setipiprant taken orally or applied topically, and what do studies show about its results? Every published human study of setipiprant used oral tablets; no peer-reviewed trial has tested a topical version. Results were inconsistent in seasonal allergic rhinitis, and the one controlled hair-loss trial (DuBois 2021, 169 men, 24 weeks) found no significant regrowth. It is an experimental, unapproved compound.

learn zinc PCA

Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.

learn Ecklonia Cava

Is Ecklonia Cava better taken orally or applied topically for thinning hair? There is no human trial of Ecklonia cava for hair loss by either route, so neither oral nor topical use is established; the published work is laboratory studies on human cells and topical studies in mice.