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Did you mean Squaric Acid Dibutylester?

Glossary Squaric Acid Dibutylester

chemical used in dermatology to treat alopecia areata

Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

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research Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata

15 citations , March 2008 in “The Journal of Dermatology”

In this case report, a patient with a history of discoid lupus erythematosus experienced an exacerbation of the condition after topical immunotherapy for alopecia areata, suggesting contact dermatitis as a potential trigger.

research Topical use of calcipotriol does not potentiate squaric acid dibutylester effectiveness in the treatment of alopecia areata

5 citations , January 1995 in “Journal of Dermatological Treatment”

This study suggests that topical calcipotriol did not significantly enhance hair growth when combined with SADBE in patients with severe alopecia areata.