Search

for
Search:

Did you mean propylene glycol?

Glossary propylene glycol

synthetic liquid that enhances skin absorption of active ingredients

Propylene glycol is a synthetic liquid substance that absorbs water and is commonly used as a solvent in pharmaceuticals, including topical treatments for hair and skin conditions. It helps active ingredients penetrate the skin more effectively and is generally considered safe for use, though some individuals may experience skin irritation.

Research

5 / 1000+ results

research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil without Propylene glycol: A 6-month, Multicentre, Real-life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The andldquo;NOMINALandrdquo; Trial

January 2021 in “Journal of clinical & experimental dermatology research”

This study found that a new propylene glycol-free 5% minoxidil lotion demonstrated good clinical efficacy and very good cosmetic acceptability and tolerability after six months of use in patients with androgenetic alopecia, showing results comparable to traditional formulations containing propylene glycol.

research The “NOMINAL” trial: Clinical efficacy, cosmetic acceptability, and local tolerability of topical 5% minoxidil lotion without propylene glycol: A 6-month, multicentre, real-life, prospective, assessor-blinded study in 196 subjects with hair loss.

January 2021 in “Medical research archives”

In this study, researchers examined a new propylene glycol-free 5% minoxidil lotion for 6 months among individuals with androgenic alopecia and found it demonstrated good clinical efficacy, with 74% showing a positive response, and very high cosmetic acceptability and tolerability, comparable to traditional formulations.

research Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss

September 2019 in “Case medical research”

research Skin deposition and permeation of finasteridein vitro: effects of propylene glycol, ethanol and sodium lauryl sulfate

5 citations , August 2014 in “Pharmaceutical Development and Technology”

In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.

research Allergic contact dermatitis to topical minoxidil solution: Etiology and treatment

123 citations , February 2002 in “Journal of The American Academy of Dermatology”

Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.

View more "topical propylene glycol" in research →

Community Join

5 / 1000+ results

community Making topical finasteride with ethanol + propylene glycol vs mixing it with topical minoxidil

2 upvotes 10 months ago

The conversation discusses two methods for making topical finasteride: using ethanol and propylene glycol or mixing it with topical minoxidil. The focus is on solubility and absorption, with a suggestion to crush pills finely and possibly mix with minoxidil at a slightly elevated temperature.

community Propylene Glycol vs Glycerin in topical finasterside?

2 upvotes 11 months ago

Switching from propylene glycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.

community Mixing Topical Finasteride: isopropyl alcohol / Propylene glycol ratio

in Finasteride/Dutasteride 2 upvotes 1 year ago

The conversation discusses adjusting the isopropyl alcohol, propylene glycol, and water ratios in a topical finasteride solution for better scalp comfort and less dandruff. The user considers using 20ml IPA, 25ml PG, and 15ml water in a 60ml bottle, moving away from mixing finasteride with topical minoxidil.

community Who make a topical minoxidil and finasteride combo without propylene glycol?

4 upvotes 1 year ago

The user is seeking a topical minoxidil and finasteride combination without propylene glycol due to scalp irritation. They are looking for a supplier in the US.

community Propylene glycol vs ethyl alcohol(70% or 96%) for topical finasteride solution. Pros and cons?

4 upvotes 2 years ago

The conversation discusses the pros and cons of using propylene glycol versus ethyl alcohol in topical solutions for finasteride and minoxidil. It questions why propylene glycol is commonly used and whether ethyl alcohol might be a better option.

View more "topical propylene glycol" in community →

Learn

1 / 26 results

learn Finasteride

Does the vehicle change how much topical finasteride is absorbed? Formulation sources describe propylene glycol and microemulsion vehicles as increasing how much topical finasteride crosses the skin, but better penetration has not been shown to mean better hair results, and it also raises systemic exposure. The vehicle and strength are decisions for a prescriber or compounding pharmacist.

View more "topical propylene glycol" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →