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Efficacy of Topical Minoxidil and Oral Spironolactone Versus Minoxidil and Finasteride in Androgenic Alopecia

research The efficacy of the combination of topical minoxidil and oral spironolactone compared with the combination of topical minoxidil and oral finasteride in women with androgenic alopecia, female and male hair loss patterns: A blinded randomized clinical trial

August 2023 in “Journal of Cosmetic Dermatology”

This study found that combining minoxidil and spironolactone was more effective for hair density and severity of hair loss in women with androgenic alopecia compared to minoxidil and finasteride, with no serious adverse effects reported.

Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

36 citations , September 2018 in “American Journal of Clinical Dermatology”

This study found that a topical combination of 0.25% finasteride and 3% minoxidil may increase hair diameter more effectively than 3% minoxidil alone in postmenopausal women with female pattern hair loss.

Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

19 citations , May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.

Comparative Efficacy of Topical Finasteride (0.25%) in Combination With Minoxidil (5%) Against 5% Minoxidil or 0.25% Finasteride Alone in Male Androgenetic Alopecia: A Pilot, Randomized Open-Label Study

research Comparative efficacy of topical finasteride (0.25%) in combination with minoxidil (5%) against 5% minoxidil or 0.25% finasteride alone in male androgenetic alopecia: A pilot, randomized open-label study

March 2023 in “International Journal of Trichology”

This study found that a combination of topical 5% minoxidil and 0.25% finasteride was more effective at improving hair density and satisfaction in men with androgenetic alopecia than either treatment alone over 24 weeks.

Evaluation of Platelet-Rich Plasma Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia

research Evaluation of Platelet-Rich Plasma (PRP) Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia

August 2024 in “Pakistan Journal of Health Sciences”

This study found that adding platelet-rich plasma (PRP) to oral finasteride was more effective in improving hair density and regrowth than combining finasteride with topical minoxidil for treating androgenic alopecia.

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community Finasteride x Minoxil Topical Hair Loss

in Finasteride/Dutasteride 9 upvotes 3 weeks ago

The user is using a combination of finasteride, minoxidil, ketoconazole, pumpkin seeds, laser therapy, PRP, dermaroller, and vitamins for hair loss. They are advised to switch to oral finasteride and be patient, as results may take up to a year, with a hair transplant as a potential future option.

community Who make a topical minoxidil and finasteride combo without propylene glycol?

4 upvotes 1 year ago

The user is seeking a topical minoxidil and finasteride combination without propylene glycol due to scalp irritation. They are looking for a supplier in the US.

community 4 months topical minoxidil + 2 months finasteride

in Minoxidil 132 upvotes 1 year ago

Topical minoxidil and oral finasteride are effectively promoting hair growth with minimal side effects, such as no impact on sex drive. Users report positive results and reduced hair shedding, with some using a combination of topical foam containing both minoxidil and finasteride.

community I take Ulo topical finasteride 0.005%, topical minoxidil, oral minoxidil 5 mg, a liquid multivitamin, collagen powder, and liquid biotin. I also microneedle with a Dr. Pen and use red light therapy.

6 upvotes 4 months ago

A 21-year-old is using a combination of topical finasteride, topical and oral minoxidil, a liquid multivitamin, collagen powder, liquid biotin, microneedling, and red light therapy to address hair thinning. They are cautious about side effects and unsure if their hair loss is due to DHT or past brushing habits.

community Would a combination of low dose oral and topical finasteride theoretically give the best outcome?

in Finasteride/Dutasteride 5 upvotes 4 months ago

Using a combination of low-dose oral and topical finasteride, along with minoxidil, may effectively manage hair loss by targeting both systemic and local DHT. Users report positive experiences with this regimen, noting good tolerability and no worsening of hair condition.

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learn Finasteride

Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.

learn Caffeine

Is it safe to combine caffeine with other topical treatments? Only one small trial has tested caffeine together with another hair-loss topical (minoxidil 2.5%), and it favoured the combination; caffeine with topical finasteride, ketoconazole or plant oils has never been studied, so no source can call those combinations safe.

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Overview

learn Mesotherapy

technique to inject very small amounts of beneficial chemicals into the scalp

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Epidermal Growth Factor

learn Scalp Micropigmentation

Can I use hair loss treatments (finasteride, minoxidil) after scalp micropigmentation? About half of clinics say finasteride can continue through scalp micropigmentation, and about half ask clients to pause topical minoxidil during the sessions and for roughly 30 days afterwards. That pause is clinic aftercare convention, not a label instruction - ask your prescriber first, because stopping minoxidil usually causes shedding.

learn Ketoconazole

Ketoconazole: Can I use it with minoxidil or finasteride? No published study has tested ketoconazole shampoo together with minoxidil and finasteride, and no interaction between them has been reported; the only direct evidence for a pairing is a ten-patient finasteride-plus-ketoconazole arm in a 2002 study, and a 2020 systematic review calls topical ketoconazole promising while asking for randomized trials.

learn Microneedling

Can microneedling make topical treatments like minoxidil work better? Microneedling can enhance the absorption and effectiveness of minoxidil.

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