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      research MON-203 Dermatological Effects Of Hormone Replacement Therapy

      October 2025 in “Journal of the Endocrine Society”
      This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

      research Biology of estrogens in skin: implications for skin aging

      187 citations , December 2005 in “Experimental Dermatology”
      This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.

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      community 19 months Topical Min/Fin - 7 months HRT

       1072 upvotes 3 months ago
      The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.

      community 9 months fin/dut + topical min + estrogen. Doing a happy dance!

       148 upvotes 1 year ago
      The post discusses a user's successful hair regrowth using finasteride, dutasteride, topical minoxidil, and estrogen over nine months. The user, who is male-to-female (mtf), reports significant regrowth and no side effects beyond typical hormone replacement therapy effects.

      community How it started and how it's going.

      in Progress Pictures  1 upvotes 1 year ago
      The user shares their hair growth progress using topical and sublingual minoxidil, dutasteride, hormone replacement therapy, and a laser comb. They report thicker hair and reduced hairline shedding, seeking advice for further thickening.

      community My 2 Years Progress (Hair Recovery)

       1465 upvotes 5 months ago
      A person shared their hair regrowth journey using HIMS topical treatments with finasteride, minoxidil, hormone replacement therapy (HRT), and microneedling. They also discussed their transition as a transgender woman and the positive impact of HRT on hair recovery.

      community Transplant Candidate? (26, Male)

       40 upvotes 8 months ago
      A 26-year-old male considering a hair transplant is using topical finasteride and minoxidil, planning to start feminizing hormone replacement therapy (HRT) with estrogen and spironolactone. Many suggest waiting to see the effects of HRT, which may significantly regrow hair, before deciding on a transplant, and recommend adding microneedling and possibly switching to oral treatments for better results.

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