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Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia

research Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia

42 citations , December 2015 in “International Journal of Clinical Pharmacology and Therapeutics”

This study found that applying a novel 0.25% finasteride solution to the scalp can effectively reduce scalp DHT levels in men with androgenetic alopecia, potentially reducing systemic side-effects.

A Cross-Sectional Randomized Comparative Study of Topical Minoxidil Solution With and Without Finasteride in Male Pattern Androgenetic Alopecia in South Indian Patients

research A cross-sectional randomized comparative study of topical minoxidil solution with and without finasteride in male pattern androgenetic alopecia in South Indian patients

1 citations , January 2018 in “International Journal of Research in Dermatology”

In this study, the therapeutic response of topical minoxidil solution was not significantly enhanced by adding topical finasteride, questioning its additional value in treating male pattern androgenetic alopecia.

research Hair Transplantation for Frontal Fibrosing Alopecia: Part of the Solution?

7 citations , September 2015 in “Actas Dermo-Sifiliográficas”

This article reviews the challenges of treating frontal fibrosing alopecia and the potential role of hair transplantation, noting the lack of effective medical treatments and uncertainty surrounding transplant outcomes.

research Hair Transplantation for Frontal Fibrosing Alopecia: Part of the Solution?

December 2015 in “Actas Dermo-Sifiliográficas”

This review addresses the challenges in treating frontal fibrosing alopecia, highlighting the limited effectiveness of medical treatments and the demand for hair transplantation despite its risks, but it reports no new clinical results.

research Male and Female Androgenetic Alopecia

June 2014

This chapter reviews the causes, prevalence, and prognosis of androgenetic alopecia and discusses treatments like topical minoxidil and systemic finasteride to stop hair loss and potentially increase hair density.

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community People call companies stupid for making very high concentration Topical Fin solutions but I think they overlook the fact that the actual absorption rate of finasteride varies greatly

in Finasteride/Dutasteride 13 upvotes 2 years ago

The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.

community Is combining topical and oral finasteride pointless

1 upvotes 9 months ago

A user is using topical finasteride, minoxidil, and oral finasteride for hair loss but hasn't seen progress yet. They are considering switching to oral finasteride only due to scalp issues from the topical solution, but are advised to continue the current regimen for at least six months to a year.

community Diluting 0.05% topical finasteride serum/oil

1 upvotes 3 years ago

The user wants to reduce their dose of topical finasteride to 0.1-0.2mg and is considering mixing 0.2ml of their current finasteride + minoxidil serum with 0.8ml of a minoxidil-only serum for better scalp coverage. They are asking for advice on whether this method is effective or if there's a better way to dilute the finasteride solution.

community Topical finasteride solution: Did my pharmacy simply dissolve finasteride tablets?

in Finasteride/Dutasteride 7 upvotes 1 year ago

A user received a topical finasteride solution from a pharmacy, which likely dissolved finasteride tablets instead of using pure finasteride powder, resulting in sediment. The user expressed dissatisfaction, expecting pure powder, and discussed the pros and cons of DIY solutions and the use of minoxidil with finasteride.

community Results after only 3.5 weeks, using topical fin/min + 1x a week microneedling.

in Progress Pictures 8 upvotes 2 years ago

A 31-year-old used topical minoxidil and finasteride with weekly microneedling for 3.5 weeks, seeing improvements in the crown and frontal areas. They are happy with the results and curious about the 3-month mark.

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Learn

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learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Thymosin Beta 4

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Finasteride

Are there really risks with topical finasteride? Reports on topical finasteride describe scalp irritation and dermatitis as the effects specific to it, and blood levels lower than the oral drug; whether systemic side effects are genuinely rarer has not been measured in a trial powered to answer it. Both forms are prescription-only and contraindicated around pregnancy.
Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.

learn Caffeine

Is it safe to combine caffeine with other topical treatments? Only one small trial has tested caffeine together with another hair-loss topical (minoxidil 2.5%), and it favoured the combination; caffeine with topical finasteride, ketoconazole or plant oils has never been studied, so no source can call those combinations safe.

learn Ketoconazole

Ketoconazole: Can I use it with minoxidil or finasteride? No published study has tested ketoconazole shampoo together with minoxidil and finasteride, and no interaction between them has been reported; the only direct evidence for a pairing is a ten-patient finasteride-plus-ketoconazole arm in a 2002 study, and a 2020 systematic review calls topical ketoconazole promising while asking for randomized trials.

learn Saw Palmetto

Is it better to take saw palmetto in capsules or use it in lotions? The evidence does not show one form is better: the only head-to-head hair study of oral saw palmetto compared it with finasteride (and finasteride did better), the topical evidence is a single uncontrolled pilot, and there is no trial comparing capsules with lotions.

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

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