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TMPRSS2

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Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations , December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations , April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research Sex Hormones in SARS-CoV-2 Susceptibility: Key Players or Confounders?

8 citations , December 2022 in “Nature Reviews Endocrinology”

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

research Sex- Or Gender-Specific Differences In The Clinical Presentation, Outcome, And Treatment Of SARS-CoV-2

22 citations , January 2021 in “Clinical Therapeutics”

Men face more severe COVID-19 outcomes, while women are more likely to have long-term symptoms.

research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

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community Adrogens and Covid-19

in Treatment 6 upvotes 5 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.