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    Did you mean SMAD signaling?
    Glossary SMAD signaling

    cellular process transmitting signals from surface to nucleus

    SMAD signaling, also known as the SMAD pathway, is a cellular process that transmits signals from the cell surface to the nucleus in response to transforming growth factor-beta (TGF-β) and related cytokines. This pathway involves SMAD proteins, which are activated by receptor kinases and then move into the nucleus to regulate gene expression. This signaling is crucial for various biological processes, including cell growth, differentiation, and development, and has implications in conditions like cancer and fibrosis.

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    1. Injectable platelet-rich fibrin promotes proliferation and trichogenic inductivityof dermal papilla cells through activating TGF-β/Smad signaling pathway Cellular and Molecular Biology · 2024 · 4 citations
    2. Kaempferol enhances hair growth by regulating JAK3/STAT6 and TGF-β/Smad signaling in human dermal papilla cells and a C57BL/6 mousemodel Records of Natural Products · 2025
    3. Human bone marrow mesenchymal stem cells-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway Research Square (Research Square) · 2020
    4. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    5. Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway Stem Cell Research & Therapy · 2020 · 139 citations
    6. Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis Clinical Cosmetic and Investigational Dermatology · 2025
    7. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    8. Polysulfonic acid mucopolysaccharide exerts anti scarring effect in rats through modulation of TGF β 1/Smad signaling pathway Tropical Journal of Pharmaceutical Research · 2023 · 1 citations
    9. Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway International Journal of Molecular Sciences · 2026
    10. 4-<i>O</i>-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling Biomolecules & Therapeutics · 2017 · 5 citations
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