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Glossary Testosterone Production

process by which the body generates the hormone testosterone

Testosterone production, also known as testosterone synthesis or androgen production, refers to the process by which the body generates testosterone, a key male sex hormone. This process primarily occurs in the testes in men and in smaller amounts in the ovaries in women and the adrenal glands in both sexes. Testosterone plays a crucial role in the development of male reproductive tissues, the maintenance of muscle mass, bone density, and the regulation of libido. The production is regulated by the hypothalamus and pituitary gland through a feedback loop involving luteinizing hormone (LH).

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Research

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research Production rates of testosterone and of dihydrotestosterone in female pattern hair loss

17 citations , July 2003 in “Metabolism-clinical and Experimental”

This study found that young women with female-pattern hair loss exhibit increased testosterone production rates while dihydrotestosterone production rates remain within or below the normal range.

research CHRONIC TREATMENT REGIMENS FOR HIRSUTISM IN WOMEN: EFFECT ON BLOOD PRODUCTION RATES OF TESTOSTERONE AND ON HAIR GROWTH

29 citations , May 1975 in “Clinical Endocrinology”

In this study, treatments combining betamethasone and anovulatory steroids significantly reduced testosterone production in women with hirsutism, with many reporting improved hirsutism and acne, although clinical benefit did not consistently correlate with testosterone reduction.

research The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results

August 2013 in “Fertility and Sterility”

This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

10 citations , November 1997 in “British Journal of Dermatology”

This study found that the non-steroidal antiandrogen RU58841 increased hair growth rates and promoted hair cycle initiation in balding human scalp grafts on testosterone-conditioned nude mice, indicating a positive effect on hair growth.

research Androgen metabolism in hirsute patients treated with cyproterone acetate

64 citations , March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

In this study, cyproterone acetate combined with estradiol dramatically improved hirsutism symptoms and significantly reduced plasma testosterone and androstenedione levels in patients over periods of up to three years.

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community Rate my MPB Genetics: Can I run Primobolan/Masteron? (Detailed MyHeritage DNA Data Included)

in General 262 upvotes 5 months ago

The user is using testosterone and finasteride to prevent hair loss and is considering adding Primobolan or Masteron, which are DHT-derivatives. They are seeking advice on their genetic risk for male pattern baldness and whether they can safely use these compounds without significant hair loss.

community If you discontinued anabolic steroids (mainly Testosterone) while on Dut, would you restart seeing results?

9 upvotes 2 months ago

Discontinuing anabolic steroids like testosterone while on Dutasteride may restart hair growth cycles, as high testosterone levels can still cause hair miniaturization. Trenbolone use resulted in significant gains but also side effects like night sweats and shin pain.

community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)

in Research/Science 110 upvotes 11 months ago

Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.

community Testosterone in Reference Range Doesn't Cause Hair Loss

52 upvotes 2 years ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community Testosterone and hair loss seeming irrelevance

82 upvotes 3 years ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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