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This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.

This case study reported rare alopecia resulting from a hyaluronic acid filler injection, noting approximately 80% hair regrowth after treatment with topical minoxidil.

This study suggests that hair loss and reduced arterial blood flow after hyaluronic acid filler injection in the temporal region may result from arterial compression rather than intra-arterial occlusion.

This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.

This study found that while hyaluronic acid fillers can enhance facial balance and aesthetics, particularly in the temple area, they carry significant risks like vascular occlusion and blindness, highlighting the need for careful technique and product selection to ensure safety.