July 2025 in “Journal of Cosmetic and Laser Therapy” This case study reported rare alopecia resulting from a hyaluronic acid filler injection, noting approximately 80% hair regrowth after treatment with topical minoxidil.
4 citations
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May 2023 in “JAAD case reports” This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.
4 citations
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October 2022 in “Aesthetic surgery journal” This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.
April 2024 in “Journal of applied cosmetology” This study found that while hyaluronic acid fillers can enhance facial balance and aesthetics, particularly in the temple area, they carry significant risks like vascular occlusion and blindness, highlighting the need for careful technique and product selection to ensure safety.
3 citations
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November 2022 in “Facial plastic surgery & aesthetic medicine” In this study, researchers introduced an ultrasound-guided technique for injecting hyaluronic acid fillers into the temple area to enhance safety and precision by visualizing filler placement in the interfascial space.