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research PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus

71 citations , May 2019 in “Rheumatology”

This study observed that PD-1+CXCR5-CD4+T peripheral helper cells are significantly elevated in patients with systemic lupus erythematosus and are correlated with disease activity indicators, suggesting their potential role in lupus pathogenesis.

research Real-life Data for Tenofovir Alafenamide Fumarate Treatment of Hepatitis B: the Pythagoras Cohort

5 citations , March 2021 in “Hepatitis Monthly”

This study found that tenofovir alafenamide fumarate (TAF) is an effective and safer alternative to tenofovir disoproxil fumarate (TDF) for chronic hepatitis B, with fewer long-term side effects like nephrotoxicity and decreased bone density.

research Oral tofacitinib: a promising treatment in atopic dermatitis, alopecia areata and vitiligo

37 citations , October 2017 in “Clinical and Experimental Dermatology”

This article discusses the potential of oral tofacitinib as a treatment for atopic dermatitis, alopecia areata, and vitiligo, without presenting new clinical results.

research Alopecia Areata: A Complex Cytokine Driven Disease

3 citations , October 2020 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

This research discusses the complex immune pathogenesis of alopecia areata and highlights the success of Jak inhibitors and IL-4Rα antagonists, while IL-17A and PDE4 inhibitors showed limited efficacy; controlled trials are advocated to better understand cytokine involvement.

research 176 Myeloid cell-specific deletion of mTOR suppresses psoriasis-like skin inflammation in C57BL/6 mice

April 2023 in “Journal of Investigative Dermatology”

This study reports that CD200R expression is significantly reduced in a mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.

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Community Join

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community Veradermics VDPHL01: why isn’t anyone talking about it?

in Treatment 42 upvotes 1 year ago

Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

community Don't stop taking minoxidil no matter what

in Minoxidil 9 upvotes 2 years ago

The conversation is about hair loss treatments, specifically minoxidil, finasteride, and dutasteride. The main advice is to start with finasteride and never stop minoxidil once started, as stopping can lead to significant hair loss.

community Why don’t finasteride gummies exist?

2 years ago

The conversation discusses the idea of creating finasteride gummies for hair loss treatment, with some users expressing skepticism about their effectiveness compared to pills. Concerns include the potential for reduced drug delivery in gummy form and the risk of children mistaking them for candy.

community Blaming Finasteride doesn't help you solve anything: dry eyes

51 upvotes 1 year ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

community Why doctors don't want to prescribe finisteride? UK

in Finasteride/Dutasteride 4 upvotes 5 months ago

Doctors in the UK are hesitant to prescribe finasteride for hair loss, leading many to seek it from online pharmacies. Users discuss side effects and alternative treatments like minoxidil, with some opting for online purchases due to ease and availability.

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Learn

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learn Thymosin Beta 4

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Dutasteride

Dutasteride: Why don't some doctors prescribe it if it's stronger than finasteride? Some doctors avoid prescribing dutasteride due to its higher risk of side effects.

learn Scalp Micropigmentation

Why can't I see my scalp micropigmentation after a week? Initial fading of scalp micropigmentation is normal and density improves with subsequent sessions.

learn Hair Transplant

What happens if I don't have enough donor hair for a hair transplant? Body hair or beard hair can be used if scalp donor hair is insufficient.

learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

learn Redensyl

What does Redensyl do that other natural ingredients don't? Redensyl uniquely targets hair follicle stem cells to reactivate hair growth.

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