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a topical anti-androgen with less systemic involvement
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5 / 14 resultslearn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
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learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
Research
5 / 1000+ resultsresearch Scalp Sarcoidosis with Systemic Involvement: A Case Report and Literature Review
Scalp sarcoidosis can cause hair loss and needs accurate diagnosis and treatment with specific medications.
research Alopecia as a Systemic Disease
Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
research Sarcoidosis: Are There Differences in Your Skin of Color Patients?
Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.
research Single Lesion of Sarcoidosis Presenting as Cicatricial Alopecia: A Rare Report from India
Sarcoidosis can cause scarring hair loss on the scalp, which is rare.
research Sarcoidosis Presenting as Frontal Fibrosing Alopecia: A Master Mimicker or a Coincidental Finding?
Sarcoidosis can mimic other skin disorders, making diagnosis challenging.
Community Join
5 / 1000+ resultscommunity A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Topical formulations, natural products, and CAM therapies are being used to treat Androgenic alopecia to avoid side effects of Finasteride and Minoxidil. The review covers various low-risk, alternative treatment options.
community How much Minoxidil goes systemic?
The conversation is about the systemic absorption of Minoxidil and the potential switch from topical to oral Minoxidil due to its effectiveness. The user considers oral Minoxidil after experiencing no side effects from a year of using 15% topical Minoxidil.
community Does ketoconazole reduce systemic DHT by much?
Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.
community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride
Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.
community If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.