learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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forProducts matching "systemic dht"
Tracking 4 products like 100 RU58841 Powder, 123 Polaris minoxidil shampoo NR02, 125 Polaris Research NR08 7% and 127 Polaris Research NR11 12% Minoxidil Sulfate from by companies like MinoxidilMax and Minoxidil Express. View all 4 products »Learn
5 / 8 resultslearn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
Research
5 / 1000+ results
research Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia
The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors
The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
Community Join
5 / 992 resultscommunity Lowering DHT vs measured level and topical scalp treatment issues
The conversation discusses the effects of lowering DHT on hair loss and the importance of monitoring DHT levels during treatment. The user suggests that individual responses to DHT and hair loss treatments vary, and expresses a preference for topical treatments over oral medications due to concerns about systemic DHT reduction.
community Does Topical Finasteride Directly Reducing Scalp DHT?
Topical finasteride reduces scalp DHT, with some going systemic. Using 0.025% at 1ml per day can stabilize hair loss without side effects.
community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)
A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.
community Sulforaphane Topical to Degrade DHT - For People Who Want to Try the Theory that Explains Everything
A user suggests making a potent sulforaphane topical to degrade DHT and promote hair growth. Another user notes that sulforaphane's low molecular weight might also lower systemic DHT.
community Has Anyone Heard About Ethossomal Finasteride? 6x Finasteride Delivery in Hair Folicule?
A user is considering switching from oral to topical finasteride to reduce systemic DHT impact and is exploring ethossomal finasteride for better skin penetration and potential hair regrowth. They found ethossomal finasteride in Brazil and are seeking opinions on its effectiveness compared to other topical delivery methods.