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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

    Research

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      community Anyone wanna try and interview the developers of RU?

      in Research/Science  82 upvotes 3 years ago
      The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  449 upvotes 2 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community PYRILUTAMIDE KX-826 experience

      in Research/Science  95 upvotes 2 years ago
      A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

      community Why haven’t we seen anything about this

      in Research/Science  18 upvotes 4 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.