community PP405 gets its generic name - Suvomipic
Suvomipic, previously known as PP405, is progressing to Phase 3 trials for hair loss treatment. Its effectiveness compared to existing treatments like Minoxidil and Finasteride is still uncertain.
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5 / 395 resultsresearch Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3
This study reported that UVR induced PKCε phosphorylation of Stat3 in transgenic mice, suggesting a role in enhancing sensitivity to UVR-related skin cancer development.
research The Senescence–Stemness Alliance – A Cancer-Hijacked Regeneration Principle
This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.
research Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids
In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
research H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers
This study observed that the loss of H3K9me3, via the ablation of Suv39h1, Suv39h2, and Setdb1 in embryonic mouse epidermis, disrupts skin development processes such as keratinocyte differentiation and hair follicle formation, highlighting H3K9me3's crucial role in epidermal morphogenesis.
research Ultraviolet-Induced Fluorescence and Sub-Ultraviolet Reflectance Dermatoscopy of Grover’s Disease (Transient Acantholytic Dermatosis): a Retrospective Single-Center Cohort Study
In this study, UVFD and sUVRD techniques revealed distinctive characteristics of GD lesions, suggesting that GD might be more common in younger individuals and females than previously thought, possibly due to underdiagnosis. Incorporating dermatoscopy in exams may help improve GD detection and management.
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1 / 1 resultslearn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
Experts
4 / 4 results- 79
DermatologistDr. Suvina Attavar, MBBS, DVD, IFAAD
Bengaluru, Karnataka, India
- SMP Specialist
Suvituulia Kangasmuukko
Tampere, Finland
- 85Hair Transplant Surgeon
Dr. Saroj Suvanasuthi, MD, PhD
Nonthaburi, Thailand
- Hair Transplant Surgeon
Dr. Sarocha Suvarnasutthi, American Board of Hair Restoration Surgery, Certificate of Dermoscopy, Skin cancer College, Sydney, Australia, ประกาศนียบัตรแพทย์ผู้เชี่ยวชาญเฉพาะทางสาขาโรคเส้นผม และการผ่าตัดปลูกถ่ายเส้นผม ศิริราชพยาบาล มหาวิทยาลัย, วุฒิบัตรผู้เชี่ยวชาญสาขาตจวิทยา แพทยส
Pak Kret, Thailand
